SCHEMBL28906915

SCHEMBL28906915

COc1ccccc1CNc1ccc(F)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.64
L3MBTL1 Q9Y468 4/20 0.64
MAPT P10636 7/20 0.61
GAA P10253 5/20 0.61
ALDH1A1 P00352 5/20 0.61
TDP1 Q9NUW8 3/20 0.61
HTT P42858 3/20 0.61
KDM4E B2RXH2 3/20 0.61
ALOX15 P16050 1/20 0.61
TSHR P16473 1/20 0.61
MAPK1 P28482 1/20 0.61
KMT2A Q03164 6/20 0.58
MEN1 O00255 4/20 0.58
LMNA P02545 2/20 0.55
THRB P10828 2/20 0.53
BLM P54132 2/20 0.53
RECQL P46063 1/20 0.53
ATM Q13315 1/20 0.53
PLEC Q15149 1/20 0.53
TP53 P04637 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30287924 0.87 HIF1A (0.74) HIF1AL3MBTL1MAPTGAAALDH1A1
SCHEMBL10388545 0.87 HIF1A (0.74) HIF1AL3MBTL1MAPTGAAALDH1A1
SCHEMBL2979268 0.85 HIF1A (0.62) HIF1AL3MBTL1MAPTGAAALDH1A1
Hydrochloric Acid SCHEMBL2987335 0.83 HIF1A (0.61) HIF1AL3MBTL1MAPTGAAALDH1A1
SCHEMBL2469342 0.82 HIF1A (0.59) HIF1AL3MBTL1MAPTGAAALDH1A1
SCHEMBL1645842 0.81 HIF1A (0.58) HIF1AL3MBTL1MAPTGAAALDH1A1
SCHEMBL15400259 0.81 APLNR (0.61) HIF1AMAPTGAAALDH1A1TDP1
SCHEMBL4820844 0.80 HIF1A (0.72) HIF1AL3MBTL1MAPTGAAALDH1A1
SCHEMBL6481036 0.79 MEN1 (0.52) HIF1AL3MBTL1MAPTGAAALDH1A1
SCHEMBL11213118 0.79 L3MBTL1 (0.58) HIF1AL3MBTL1MAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112206777-B Preparation method and application of carbonized octahedral material HKUST-1-400 三峡大学 2022-03-18 CN disclosed
CN-112206777-A Preparation method and application of carbonized octahedral material HKUST-1-400 三峡大学 2021-01-12 CN disclosed