Acetophenone

Acetophenone

SCHEMBL28907151

CC(=O)c1ccccc1.CC(C)CCOC(=O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.48
HSD17B10 Q99714 3/20 0.47
MAPK1 P28482 2/20 0.47
PKM P14618 2/20 0.47
LMNA P02545 2/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
MAPT P10636 2/20 0.43
SLC22A1 O15245 1/20 0.42
HTT P42858 2/20 0.42
CYP19A1 P11511 1/20 0.42
MAOB P27338 1/20 0.41
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PPARA Q07869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetophenone SCHEMBL28519404 0.90 TDP1 (0.46) PPARGHSD17B10MAPK1PKMLMNA
Acetophenone SCHEMBL28512449 0.89 TDP1 (0.49) PPARGHSD17B10MAPK1PKMLMNA
Propiophenone SCHEMBL28521313 0.84 SMN1; SMN2 (0.49) PPARGHSD17B10MAPK1PKMLMNA
Acetophenone SCHEMBL28907188 0.83 ALDH1A1 (0.53) PPARGLMNASMN1; SMN2MAPTHTT
Benzoic Acid 1-(3-Methyl)Butyl Ester SCHEMBL28250108 0.81 LMNA (0.65) PPARGHSD17B10MAPK1PKMLMNA
Benzoic Acid 1-(3-Methyl)Butyl Ester SCHEMBL132524 0.81 LMNA (0.65) PPARGHSD17B10MAPK1PKMLMNA
Acetophenone SCHEMBL28521014 0.81 LMNA (0.65) LMNASMN1; SMN2MAPTHTTMAOB
SCHEMBL610683 0.80
Benzoic Acid 1-(3-Methyl)Butyl Ester SCHEMBL27674770 0.79 LMNA (0.62) PPARGHSD17B10MAPK1PKMLMNA
Acetophenone SCHEMBL28512451 0.79 LMNA (0.42) PPARGMAPK1LMNASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109111537-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-03-16 CN disclosed
CN-109111538-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-02-05 CN disclosed
CN-109111539-B Catalyst component for olefin polymerization and catalyst thereof 中国石油化工股份有限公司 2021-02-05 CN disclosed