SCHEMBL28907313

SCHEMBL28907313

Cc1ccccc1-c1cn(Cc2ccccc2)nn1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 5/20 0.64
NPC1 O15118 1/20 0.60
RAB9A P51151 1/20 0.60
CCNK O75909 1/20 0.52
CDK12 Q9NYV4 1/20 0.52
ALDH1A1 P00352 1/20 0.51
LMNA P02545 1/20 0.51
HDAC8 Q9BY41 3/20 0.50
HDAC6 Q9UBN7 3/20 0.50
HDAC3 O15379 2/20 0.50
HDAC4 P56524 2/20 0.50
HDAC1 Q13547 2/20 0.50
HDAC7 Q8WUI4 2/20 0.50
HDAC2 Q92769 2/20 0.50
HDAC10 Q969S8 2/20 0.50
HDAC11 Q96DB2 2/20 0.50
HDAC9 Q9UKV0 2/20 0.50
HDAC5 Q9UQL6 2/20 0.50
FLT3 P36888 1/20 0.50
GSK3B P49841 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22510634 0.83 CYP19A1 (0.82) CYP19A1NPC1RAB9ACCNKCDK12
SCHEMBL29275462 0.83 CYP19A1 (0.66) CYP19A1NPC1RAB9ACCNKCDK12
SCHEMBL22868021 0.82 HDAC8 (0.53) CYP19A1NPC1RAB9ACCNKCDK12
SCHEMBL29275460 0.81 EPHB4 (0.70) CYP19A1NPC1RAB9ACCNKCDK12
SCHEMBL22868022 0.81 HDAC8 (0.55) CYP19A1NPC1RAB9AHDAC8HDAC6
SCHEMBL28202461 0.81 HDAC8 (0.52) CYP19A1NPC1RAB9AALDH1A1LMNA
SCHEMBL26874441 0.81 CYP19A1 (0.59) CYP19A1NPC1RAB9ACCNKCDK12
SCHEMBL27818294 0.79 CYP19A1 (0.60) CYP19A1NPC1RAB9ACCNKCDK12
SCHEMBL15836586 0.78 CYP19A1 (0.93) CYP19A1NPC1RAB9AHDAC8HDAC6
SCHEMBL935182 0.78 CYP19A1 (1.00) CYP19A1NPC1RAB9AHDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112275322-B Preparation method and application of supported CNTs @ NHC-Cu catalytic material 中国科学院兰州化学物理研究所 2022-01-25 CN disclosed
CN-112275322-A Preparation method and application of supported CNTs @ NHC-Cu catalytic material 中国科学院兰州化学物理研究所 2021-01-29 CN disclosed