Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.73 |
| ▸ | GAK | O14976 | 2/20 | 0.52 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.52 |
| ▸ | BUB1 | O43683 | 1/20 | 0.52 |
| ▸ | STK10 | O94804 | 1/20 | 0.52 |
| ▸ | CARS1 | P49589 | 1/20 | 0.52 |
| ▸ | MAP3K1 | Q13233 | 1/20 | 0.52 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.52 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21331758 | 0.85 | EGFR (1.00) | EGFR | |
| SCHEMBL28514262 | 0.84 | EGFR (0.76) | EGFRDYRK1ADYRK1BMAPTERBB2 | |
| SCHEMBL21333844 | 0.82 | EGFR (1.00) | EGFR | |
| SCHEMBL15928191 | 0.80 | EGFR (0.76) | EGFRGAKRIPK2BUB1STK10 | |
| SCHEMBL30167226 | 0.78 | EGFR (0.59) | EGFRERBB2ERBB4 | |
| SCHEMBL21331750 | 0.78 | EGFR (0.74) | EGFRDYRK1ADYRK1BALDH1A1 | |
| SCHEMBL21331747 | 0.77 | EGFR (1.00) | EGFR | |
| SCHEMBL17934337 | 0.76 | EGFR (1.00) | EGFRGAKRIPK2BUB1STK10 | |
| SCHEMBL21331884 | 0.76 | EGFR (0.64) | EGFRRIPK2ERBB2ERBB4 | |
| SCHEMBL30167109 | 0.76 | EGFR (0.64) | EGFRRIPK2ERBB2ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229172-B | Acyl-substituted oxazine quinazoline compound, preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2020-12-25 | — | — | CN | disclosed |