SCHEMBL28907445

SCHEMBL28907445

COc1ccc(C2Cc3cc(OC)c(OC)cc3OC2=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
LMNA P02545 1/20 0.48
MAP2K3 P46734 1/20 0.47
KMT2A Q03164 2/20 0.46
HPGD P15428 2/20 0.46
POLB P06746 1/20 0.46
RECQL P46063 1/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
SIRT2 Q8IXJ6 1/20 0.41
CYP19A1 P11511 2/20 0.41
CYP3A4 P08684 1/20 0.41
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3357789 0.85 ALOX15 (0.57) ALDH1A1MAP2K3KMT2AHPGDPOLB
SCHEMBL2069508 0.82 ALDH1A1 (0.59) ALDH1A1LMNAKMT2AHPGDPOLB
SCHEMBL705946 0.81 CYP19A1 (0.52) ALDH1A1KMT2AHPGDPOLBRECQL
SCHEMBL14389073 0.80 ALDH1A1 (0.52) ALDH1A1KMT2AHPGDPOLBRECQL
SCHEMBL28555018 0.78 CYP19A1 (0.55) ALDH1A1KMT2AHPGDMEN1MAPT
SCHEMBL11263779 0.76 ALDH1A1 (0.64) ALDH1A1KMT2AHPGDPOLBRECQL
SCHEMBL2530020 0.75 KMT2A (0.50) ALDH1A1KMT2AHPGDPOLBRECQL
SCHEMBL28580467 0.74 ALDH1A1 (0.48) ALDH1A1KMT2AHPGDPOLBMEN1
SCHEMBL28459344 0.74 KMT2A (0.39) ALDH1A1KMT2AHPGDPOLBRECQL
SCHEMBL27985597 0.71 MAPT (0.39) ALDH1A1KMT2AHPGDPOLBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112334142-A Pharmaceutical composition for wound treatment or skin activity comprising beta-glucan, glycine and 4',6, 7-trimethoxyisoflavone 株式会社贵真生物技术 2021-02-05 CN disclosed