Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MRE11 | P49959 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659457 | 1.00 | NPC1 (0.52) | NPC1CASP3RAB9ASENP7MAPT | |
| SCHEMBL28939577 | 0.88 | MRE11 (0.51) | NPC1CASP3RAB9ASENP7MAPT | |
| SCHEMBL28939576 | 0.88 | MRE11 (0.51) | NPC1CASP3RAB9ASENP7MAPT | |
| SCHEMBL28929644 | 0.86 | WNT3A (0.51) | NPC1RAB9AMAPTMRE11KMT2A | |
| SCHEMBL21224560 | 0.84 | HDAC6 (0.63) | NPC1CASP3RAB9ASENP7MAPT | |
| SCHEMBL21224715 | 0.84 | HDAC6 (0.63) | NPC1CASP3RAB9ASENP7MAPT | |
| SCHEMBL22305385 | 0.83 | MAPT (0.54) | NPC1CASP3RAB9ASENP7MAPT | |
| SCHEMBL28521855 | 0.80 | MAPT (0.71) | NPC1CASP3RAB9ASENP7MAPT | |
| SCHEMBL28521858 | 0.80 | MAPT (0.71) | NPC1CASP3RAB9ASENP7MAPT | |
| SCHEMBL22970146 | 0.80 | HDAC6 (0.67) | NPC1CASP3RAB9ASENP7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112153984-A | Compound and use thereof | 福宏治疗公司 | 2020-12-29 | — | — | CN | disclosed |