Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.53 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.53 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21224560 | 0.87 | HDAC6 (0.63) | MAPTMEN1KMT2ASTAT3ELOVL1 | |
| SCHEMBL21224715 | 0.87 | HDAC6 (0.63) | MAPTMEN1KMT2ASTAT3ELOVL1 | |
| SCHEMBL21224324 | 0.84 | SCD (0.57) | MAPTMEN1KMT2ASMN1; SMN2ADORA3 | |
| SCHEMBL21224323 | 0.84 | SCD (0.57) | MAPTMEN1KMT2ASMN1; SMN2ADORA3 | |
| SCHEMBL23729555 | 0.84 | MAPT (0.60) | MAPTMEN1KMT2ASTAT3ELOVL1 | |
| SCHEMBL22970146 | 0.83 | HDAC6 (0.67) | MAPTMEN1KMT2ASTAT3ELOVL1 | |
| SCHEMBL28907950 | 0.83 | NPC1 (0.52) | MAPTMEN1KMT2ASTAT3ELOVL1 | |
| SCHEMBL28659457 | 0.83 | NPC1 (0.52) | MAPTMEN1KMT2ASTAT3ELOVL1 | |
| SCHEMBL21225185 | 0.82 | SCD (0.54) | MAPTMEN1KMT2ASMN1; SMN2ADORA3 | |
| Trifluoroacetic Acid SCHEMBL21224201 | 0.82 | HDAC6 (0.57) | MAPTMEN1KMT2ASTAT3ELOVL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160180-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2020-08-06 | — | — | WO | disclosed |