Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439596 | 0.95 | CYP1A2 (0.36) | CYP1A2TSHRPOLBABCB1IDO1 | |
| SCHEMBL10435405 | 0.84 | POLB (0.39) | CYP1A2TSHRPOLBCYP2C19ALDH1A1 | |
| SCHEMBL9709460 | 0.82 | CYP1A2 (0.43) | CYP1A2TSHRPOLBIDO1CYP2C19 | |
| SCHEMBL28152768 | 0.80 | KMT2A (0.39) | KMT2AMDM4TP53 | |
| SCHEMBL653721 | 0.80 | POLB (0.38) | CYP1A2TSHRPOLBCYP2C19KMT2A | |
| SCHEMBL15972146 | 0.80 | POLB (0.38) | CYP1A2TSHRPOLBABCB1CYP2C19 | |
| SCHEMBL755810 | 0.78 | KMT2A (0.45) | CYP1A2TSHRKMT2AMDM4TP53 | |
| SCHEMBL9015851 | 0.77 | TSHR (0.42) | CYP1A2TSHRCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL15463430 | 0.77 | CYP1A2 (0.38) | CYP1A2TSHRPOLBCYP2C19CYP3A4 | |
| SCHEMBL4906912 | 0.77 | CYP1A2 (0.41) | CYP1A2TSHRPOLBIDO1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690856-B1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | UNIV NEW YORK STATE RES FOUND (US) | 2002-12-04 | — | — | EP | claimed |
| EP-0643056-B1 | Process for the stereospecific preparation of 1,3-dioxan-4,6-dion derivatives, precursors of chiral tetramic acids derivatives | ISOCHEM SA (FR) | 2000-02-16 | — | — | EP | claimed |
| US-5599820-A | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1997-02-04 | — | — | US | claimed |
| EP-0690856-A4 | — | UNIV NEW YORK (US) | 1996-02-07 | — | — | EP | claimed |
| EP-0690856-A1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1996-01-10 | — | — | EP | claimed |
| WO-1994022856-A1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 1994-10-13 | — | — | WO | claimed |
| US-20230293643-A1 | BRK PEPTIDES AND METHODS OF USE | CONCARLO THERAPEUTICS, INC. | 2023-09-21 | — | — | US | disclosed |
| EP-4175659-A2 | BRK PEPTIDES AND METHODS OF USE | Concarlo Holdings, LLC (US) | 2023-05-10 | — | — | EP | disclosed |
| EP-4118094-A1 | EFFICIENT PREPARATION OF DOLASTATIN AND AURISTATIN ANALOGS THROUGH A COMMON INTERMEDIATE | Sigma-Aldrich Co. LLC (US) | 2023-01-18 | — | — | EP | disclosed |
| US-11247974-B2 | Small molecules that enable cartilage rejuvenation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-02-15 | — | — | US | disclosed |
| WO-2022010914-A2 | BRK PEPTIDES AND METHODS OF USE | CONCARLO HOLDINGS, LLC (US) | 2022-01-13 | — | — | WO | disclosed |
| EP-3503871-B1 | HAIR FOLLICLE STEM CELL ACTIVATION AND HAIR GROWTH | UNIV CALIFORNIA (US) | 2021-11-17 | — | — | EP | disclosed |
| WO-2021183542-A1 | EFFICIENT PREPARATION OF DOLASTATIN AND AURISTATIN ANALOGS THROUGH A COMMON INTERMEDIATE | SIGMA-ALDRICH CO., LLC (US) | 2021-09-16 | — | — | WO | disclosed |
| US-20060041137-A1 | Kinase inhibitors | TAKEDA SAN DIEGO, INC. | 2006-02-23 | — | — | US | disclosed |
| WO-2005123672-A2 | KINASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
| WO-2005105788-A1 | INDOLE DERIVATIVES AND USE THEREOF AS KINASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2005-11-10 | — | — | WO | disclosed |
| WO-2005061519-A1 | KINASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2005-07-07 | — | — | WO | disclosed |
| US-6777535-B1 | USEFUL FOR TREATING CONDITIONS WHICH ARISE OR ARE EXACERBATED BY ANGIOGENESIS | ABBOTT LABORATORIES | 2004-08-17 | — | — | US | disclosed |
| US-5532359-A | FUNGICIDES | GENENTECH, INC. (US) | 1996-07-02 | — | — | US | disclosed |
| US-5493020-A | ANTICOAGULANTS | GENENTECH, INC. (US) | 1996-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060041137-A1 | Kinase inhibitors | MAP3K19, MAP3K20, MAP3K1 | CYP1A2 3175/4885TSHR 1322/4885POLB 943/4885 |
| US-11247974-B2 | Small molecules that enable cartilage rejuvenation | COL2A1, MKI67, RARB | CYP1A2 4774/4885TSHR 3792/4885POLB 324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.