Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015851 | 0.87 | TSHR (0.42) | CYP1A2TSHRCYP2C19MEN1KMT2A | |
| SCHEMBL10435405 | 0.85 | POLB (0.39) | CYP1A2TSHRCYP2C19POLBMEN1 | |
| SCHEMBL755810 | 0.84 | KMT2A (0.45) | CYP1A2TSHRKMT2A | |
| SCHEMBL4906912 | 0.83 | CYP1A2 (0.41) | CYP1A2TSHRCYP2C19POLBKMT2A | |
| SCHEMBL3159758 | 0.82 | CYP1A2 (0.35) | CYP1A2TSHRCYP2C19POLBALDH1A1 | |
| SCHEMBL2890843 | 0.82 | CYP1A2 (0.39) | CYP1A2TSHRCYP2C19POLBKMT2A | |
| SCHEMBL653721 | 0.81 | POLB (0.38) | CYP1A2TSHRCYP2C19POLBKMT2A | |
| SCHEMBL10937190 | 0.80 | TUBB4A (0.43) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL28152768 | 0.79 | KMT2A (0.39) | KMT2A | |
| SCHEMBL19465642 | 0.79 | CYP1A2 (0.46) | CYP1A2TSHRCYP2C19PIN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021372-A1 | CRF ANALOGS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-12-10 | — | — | WO | disclosed |