Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 16/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 16/20 | 0.72 |
| ▸ | CASP3 | P42574 | 1/20 | 0.72 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.72 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.72 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 11/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 7/20 | 0.65 |
| ▸ | POLB | P06746 | 4/20 | 0.65 |
| ▸ | CCR6 | P51684 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.61 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | XBP1 | P17861 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11053433 | 0.85 | MEN1 (0.62) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL11053435 | 0.85 | MEN1 (0.62) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL28908620 | 0.81 | MAPT (0.62) | MEN1KMT2ASENP7MAPTNPC1 | |
| SCHEMBL3123362 | 0.81 | MEN1 (0.78) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL3123360 | 0.81 | MEN1 (0.78) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL3361105 | 0.80 | MEN1 (1.00) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL3361108 | 0.80 | MEN1 (1.00) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL27898236 | 0.78 | MEN1 (0.73) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL10421075 | 0.78 | MEN1 (0.73) | MEN1KMT2ACASP3SENP8SENP7 | |
| SCHEMBL13875560 | 0.77 | KMT2A (0.88) | MEN1KMT2ACASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9779901-B2 | High temperature material compositions for high temperature thermal cutoff devices | THERM-O-DISC, INCORPORATED (US) | 2017-10-03 | — | — | US | disclosed |
| US-20150162153-A1 | HIGH TEMPERATURE MATERIAL COMPOSITIONS FOR HIGH TEMPERATURE THERMAL CUTOFF DEVICES | THERM-O-DISC, INCORPORATED (US) | 2015-06-11 | — | — | US | disclosed |
| US-8961832-B2 | High temperature material compositions for high temperature thermal cutoff devices | THERM-O-DISC, INCORPORATED (US) | 2015-02-24 | — | — | US | disclosed |
| US-20120121795-A1 | HIGH TEMPERATURE MATERIAL COMPOSITIONS FOR HIGH TEMPERATURE THERMAL CUTOFF DEVICES | THERM-O-DISC, INCORPORATED (US) | 2012-05-17 | — | — | US | disclosed |
| CN-101685733-A | High-temperature thermal fuse device | THERM O DISC INC | 2010-03-31 | — | — | CN | disclosed |
| US-20100033295-A1 | HIGH TEMPERATURE THERMAL CUTOFF DEVICE | THERM-O-DISC, INCORPORATED (US) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121795-A1 | HIGH TEMPERATURE MATERIAL COMPOSITIONS FOR HIGH TEMPERATURE THERMAL CUTOFF DEVICES | HTT, HTR1A, TPH1 | MEN1 897/4885KMT2A 1408/4885CASP3 2663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.