Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GALR2 | O43603 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468543 | 0.88 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MAPTCRHBPCRHR2 | |
| SCHEMBL1621780 | 0.88 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MAPTCRHBPCRHR2 | |
| SCHEMBL14457140 | 0.86 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1MAPTCRHBPCRHR2 | |
| SCHEMBL17446891 | 0.85 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MAPTCRHBPCRHR2 | |
| SCHEMBL25295115 | 0.83 | GAA (0.43) | ALDH1A1L3MBTL1MAPTCRHBPCRHR2 | |
| SCHEMBL30484114 | 0.83 | GAA (0.43) | ALDH1A1L3MBTL1MAPTCRHBPCRHR2 | |
| SCHEMBL17781100 | 0.81 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MAPTCRHBPCRHR2 | |
| SCHEMBL2126106 | 0.80 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTGAASMN1; SMN2 | |
| SCHEMBL13457793 | 0.79 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1MAPTCRHBPCRHR2 | |
| SCHEMBL31213812 | 0.79 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1MAPTCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298176-A | Compounds and their use in the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-11-04 | — | — | CN | disclosed |