SCHEMBL2890917

SCHEMBL2890917

Cn1c(-c2ccc(Br)cc2F)nc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.49
ALDH1A1 P00352 9/20 0.49
NPC1 O15118 8/20 0.49
SMN1; SMN2 Q16637 7/20 0.49
TP53 P04637 5/20 0.49
PKM P14618 4/20 0.49
TSHR P16473 3/20 0.49
USP2 O75604 1/20 0.49
MAPT P10636 8/20 0.48
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
HTT P42858 3/20 0.48
KDM4E B2RXH2 8/20 0.47
METAP2 P50579 1/20 0.46
METAP1 P53582 1/20 0.46
ALOX15 P16050 3/20 0.46
GAA P10253 3/20 0.46
HSD17B10 Q99714 3/20 0.46
HPGD P15428 4/20 0.44
LMNA P02545 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3508179 0.89 RAB9A (0.51) RAB9AALDH1A1NPC1SMN1; SMN2TP53
SCHEMBL6298381 0.85 SMN1; SMN2 (0.49) RAB9AALDH1A1NPC1SMN1; SMN2TP53
SCHEMBL27611222 0.84 SMN1; SMN2 (0.48) RAB9AALDH1A1NPC1SMN1; SMN2TP53
SCHEMBL30663907 0.83 RAB9A (0.53) RAB9AALDH1A1NPC1SMN1; SMN2TP53
SCHEMBL26603179 0.83 RAB9A (0.53) RAB9AALDH1A1NPC1SMN1; SMN2TP53
SCHEMBL20867465 0.82 RAB9A (0.53) RAB9AALDH1A1NPC1SMN1; SMN2TP53
SCHEMBL3714642 0.82 PDE10A (0.56) RAB9AALDH1A1NPC1SMN1; SMN2TP53
SCHEMBL12759790 0.80 NPC1 (0.49) RAB9AALDH1A1NPC1SMN1; SMN2TP53
SCHEMBL1624942 0.80 RAB9A (0.51) RAB9AALDH1A1NPC1SMN1; SMN2TP53
SCHEMBL29978223 0.80 RAB9A (0.51) RAB9AALDH1A1NPC1SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US disclosed
EP-1799677-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS Ranbaxy Laboratories Limited (IN) 2007-06-27 EP disclosed
WO-2006038100-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2006-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS OXA1L, PDK4, MLYCD RAB9A 4328/4885ALDH1A1 944/4885NPC1 3916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.