Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4927010 | 0.78 | SMN1; SMN2 (0.35) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL4925010 | 0.78 | KMT2A (0.38) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL4927318 | 0.78 | KDM4E (0.34) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL4926477 | 0.78 | KDM4E (0.34) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL4926952 | 0.78 | ALDH1A1 (0.36) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL4927715 | 0.78 | KMT2A (0.38) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL10770364 | 0.78 | MAPT (0.38) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL58486 | 0.67 | TSHR (0.46) | KMT2AALDH1A1GAATDP1LMNA | |
| SCHEMBL450992 | 0.65 | — | — | |
| SCHEMBL8013186 | 0.64 | NCOA1 (0.44) | MEN1KMT2AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466177-B2 | Treating and preventing viral infections | THE UAB RESEARCH FOUNDATION (US) | 2013-06-18 | — | — | US | disclosed |
| US-20100286212-A1 | Treating and Preventing Viral Infections | THE UAB RESEARCH FOUNDATION (US) | 2010-11-11 | — | — | US | disclosed |
| EP-2217573-A1 | TREATING AND PREVENTING VIRAL INFECTIONS | The UAB Research Foundation (US) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009059243-A1 | TREATING AND PREVENTING VIRAL INFECTIONS | THE UAB RESEARCH FOUNDATION (US) | 2009-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286212-A1 | Treating and Preventing Viral Infections | HAVCR2, IRF3, MAVS | MEN1 3172/4885KMT2A 3809/4885KDM4E 4251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.