Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877620 | 0.87 | KMT2A (0.41) | EIF4A3KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL31219118 | 0.82 | XDH (0.51) | EIF4A3KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL16235851 | 0.82 | XDH (0.51) | EIF4A3KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL24198716 | 0.79 | EIF4A3 (0.49) | EIF4A3KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL8959587 | 0.78 | KDM4E (0.67) | EIF4A3KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL23441333 | 0.77 | HRH4 (0.50) | RAB9ANPC1MEN1KMT2AHRH3 | |
| SCHEMBL832227 | 0.77 | RAB9A (0.67) | KDM4EALDH1A1HPGDLMNARAB9A | |
| SCHEMBL829726 | 0.77 | HRH4 (0.55) | KDM4EALDH1A1HPGDLMNARAB9A | |
| SCHEMBL22529436 | 0.76 | EIF4A3 (0.53) | EIF4A3KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL318243 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1HPGDLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115720578-A | Tricyclic derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-112533898-A | Heterocyclic compounds | 日商泛美克斯股份有限公司 | 2021-03-19 | — | — | CN | disclosed |