Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532356 | 0.73 | MAPT (0.47) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL6295286 | 0.73 | AKT1 (0.48) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL22268377 | 0.71 | ALDH1A1 (0.50) | MAPTALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL213829 | 0.70 | ALDH1A1 (0.51) | MAPTALDH1A1KMT2ASMN1; SMN2MAPK1 | |
| (Diphenylmethylidene)Amino Benzoate SCHEMBL92010 | 0.68 | ALDH1A1 (0.66) | MAPTRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL14278328 | 0.67 | ALDH1A1 (0.64) | MAPTRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL11333722 | 0.67 | ALDH1A1 (0.50) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL24961282 | 0.66 | POLB (0.49) | MAPTALDH1A1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL15969360 | 0.66 | ELANE (0.49) | MAPTALDH1A1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL26908691 | 0.66 | MAPT (0.55) | MAPTRAB9ANPC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |