SCHEMBL28909326

SCHEMBL28909326

Fc1ccn2cc(-c3ccccc3)nc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 1/20 0.61
NPC1 O15118 8/20 0.59
RAB9A P51151 7/20 0.59
BACE1 P56817 2/20 0.57
BACE2 Q9Y5Z0 2/20 0.57
ALDH1A3 P47895 4/20 0.56
SCD O00767 1/20 0.56
PLK4 O00444 1/20 0.53
JAK2 O60674 1/20 0.53
RET P07949 1/20 0.53
PIM1 P11309 1/20 0.53
FGFR1 P11362 1/20 0.53
FLT1 P17948 1/20 0.53
KDR P35968 1/20 0.53
FLT3 P36888 1/20 0.53
PIM3 Q86V86 1/20 0.53
ALK Q9UM73 1/20 0.53
ALDH1A1 P00352 2/20 0.51
ALDH1A2 O94788 1/20 0.51
TP53 P04637 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22615001 0.84 RAB9A (0.60) TLR9NPC1RAB9ABACE1BACE2
SCHEMBL13325776 0.83 TLR9 (0.65) TLR9NPC1RAB9AALDH1A3SCD
SCHEMBL13325781 0.81 SCD (0.65) TLR9NPC1RAB9AALDH1A3SCD
SCHEMBL8257038 0.80 TLR9 (0.61) TLR9NPC1RAB9AALDH1A3SCD
SCHEMBL1458358 0.80 TLR9 (0.67) TLR9NPC1RAB9AALDH1A3SCD
SCHEMBL6393875 0.80 SMN1; SMN2 (0.79) TLR9NPC1RAB9AALDH1A3SCD
SCHEMBL28396792 0.80 TLR9 (0.61) TLR9NPC1RAB9AALDH1A3SCD
SCHEMBL28535736 0.80 TLR9 (0.57) TLR9NPC1RAB9AALDH1A3SCD
Hydrochloric Acid SCHEMBL16341016 0.79 TLR9 (0.65) TLR9NPC1RAB9AALDH1A3SCD
SCHEMBL30309564 0.78 HDAC6 (0.65) TLR9NPC1RAB9ABACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184664-A Synthetic method of naphtho [1',2', 4,5] imidazo [1,2-a ] pyridine fluorescent compound 阜阳师范大学 2024-06-14 CN disclosed
CN-112375102-B Preparation method of visible light catalyzed phosphonylation imidazopyridine compound 郑州大学 2022-05-20 CN disclosed
CN-112375102-A Preparation method of visible light catalyzed phosphonylation imidazopyridine compound 郑州大学 2021-02-19 CN disclosed