Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | SCD | O00767 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL913809 | 0.85 | SCD (0.79) | HDAC6SCDKDM4EALDH1A1MEN1 | |
| SCHEMBL30966874 | 0.85 | SMN1; SMN2 (0.71) | HDAC6SCDKDM4EALDH1A1MEN1 | |
| SCHEMBL915138 | 0.83 | SCD (0.78) | HDAC6SCDKDM4EALDH1A1MEN1 | |
| Zolimidine SCHEMBL932657 | 0.79 | HDAC6 (1.00) | HDAC6SCDKDM4EALDH1A1MEN1 | |
| SCHEMBL22615001 | 0.79 | RAB9A (0.60) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL913165 | 0.78 | SCD (0.76) | HDAC6SCDKDM4EALDH1A1MEN1 | |
| SCHEMBL28909326 | 0.78 | TLR9 (0.61) | SCDKDM4EALDH1A1KMT2ANPC1 | |
| Zolimidine SCHEMBL29405502 | 0.78 | HDAC6 (0.97) | HDAC6SCDKDM4EALDH1A1MEN1 | |
| SCHEMBL914100 | 0.78 | SCD (0.74) | HDAC6SCDKDM4EALDH1A1MEN1 | |
| SCHEMBL14067368 | 0.75 | TLR9 (0.48) | SCDKDM4EALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096717-A | Imidazo [1,2-a ] pyridine and [1,2,4] triazolo [1,5-a ] pyridine derivatives as TLR9 inhibitors for the treatment of fibrosis | 百时美施贵宝公司 | 2023-05-09 | — | — | CN | claimed |
| CN-116096717-A | Imidazo [1,2-a ] pyridine and [1,2,4] triazolo [1,5-a ] pyridine derivatives as TLR9 inhibitors for the treatment of fibrosis | 百时美施贵宝公司 | 2023-05-09 | — | — | CN | disclosed |