Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904518 | 0.98 | — | — | |
| SCHEMBL27790504 | 0.81 | TSHR (0.38) | LMNATSHRHCAR2CYP2D6SMN1; SMN2 | |
| SCHEMBL29433283 | 0.80 | LMNA (0.45) | LMNATSHRHCAR2CYP2D6MAPT | |
| SCHEMBL28236712 | 0.79 | CHRNB2 (0.32) | TSHR | |
| SCHEMBL9729698 | 0.78 | — | — | |
| SCHEMBL207281 | 0.76 | — | — | |
| SCHEMBL16612904 | 0.76 | LMNA (0.42) | LMNATSHRHCAR2CYP2D6MAPT | |
| SCHEMBL6231322 | 0.76 | — | — | |
| SCHEMBL9177236 | 0.74 | LMNA (0.45) | LMNATSHRHCAR2CYP2D6MAPT | |
| SCHEMBL8750063 | 0.74 | LMNA (0.50) | LMNATSHRHCAR2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409381-B | Piperacillin sodium and tazobactam sodium co-amorphous substance and preparation method thereof | 山东安信制药有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-112409381-A | Piperacillin sodium and tazobactam sodium co-amorphous substance and preparation method thereof | 山东安信制药有限公司 | 2021-02-26 | — | — | CN | disclosed |