Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 5/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2453463 | 0.79 | HTT (0.33) | ABCC8KCNJ11MAPTCYP1A2CYP2D6 | |
| SCHEMBL29129844 | 0.78 | MEN1 (0.34) | ABCC8KCNJ11MAPTALDH1A1HTT | |
| SCHEMBL6684736 | 0.77 | ADORA2A (0.42) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL28547173 | 0.77 | HTT (0.32) | ABCC8KCNJ11MAPTCYP1A2CYP2D6 | |
| SCHEMBL28581246 | 0.77 | CCNE2 (0.36) | ABCC8KCNJ11MAPTCYP1A2CYP2D6 | |
| SCHEMBL12335518 | 0.74 | ADORA2A (0.31) | CYP1A2CYP2D6CYP2C9CYP2C19HTT | |
| SCHEMBL29277393 | 0.67 | MAPT (0.32) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10420191 | 0.65 | DYRK1A (0.42) | MAPTCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12334710 | 0.65 | CCNE2 (0.37) | MAPTALDH1A1 | |
| SCHEMBL15560478 | 0.65 | MAPT (0.38) | MAPTCYP1A2CYP2D6CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8211252-B2 | Furazane derivatives, preparation thereof and energetic compositions containing them | EURENCO (FR) | 2012-07-03 | — | — | US | claimed |
| US-20100132856-A1 | FURAZANE DERIVATIVES, PREPARATION THEREOF AND ENERGETIC COMPOSITIONS CONTAINING THEM | SNPE MATERIAUX ENERGETIQUES (FR) | 2010-06-03 | — | — | US | claimed |
| US-8211252-B2 | Furazane derivatives, preparation thereof and energetic compositions containing them | EURENCO (FR) | 2012-07-03 | — | — | US | disclosed |
| US-20100132856-A1 | FURAZANE DERIVATIVES, PREPARATION THEREOF AND ENERGETIC COMPOSITIONS CONTAINING THEM | SNPE MATERIAUX ENERGETIQUES (FR) | 2010-06-03 | — | — | US | disclosed |
| EP-2125796-A1 | FURAZANE DERIVATIVES, PREPARATION THEREOF AND ENERGETIC COMPOSITIONS CONTAINING THEM | SNPE Matériaux Energétiques (FR) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008102092-A1 | FURAZANE DERIVATIVES, PREPARATION THEREOF AND ENERGETIC COMPOSITIONS CONTAINING THEM | SNPE MATERIAUX ENERGETIQUES (FR) | 2008-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100132856-A1 | FURAZANE DERIVATIVES, PREPARATION THEREOF AND ENERGETIC COMPOSITIONS CONTAINING THEM | NOX5, COX5A, TXN2 | ABCC8 1734/4885KCNJ11 711/4885MAPT 4307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.