SCHEMBL28909686

SCHEMBL28909686

O=P(O)(Cl)Cl.OC(F)(F)c1ccc(F)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28909637 0.91 CES2 (0.36) CES2CES1PGK1PGK2PTPN1
SCHEMBL1201613 0.86 CES2 (0.39) CES2CES1
SCHEMBL28913701 0.81 CES2 (0.33) CES2CES1
SCHEMBL28913721 0.79 CES2 (0.34) CES2CES1
SCHEMBL3219002 0.77 PGK1 (0.48) CES2CES1PGK1PGK2PTPN1
SCHEMBL11286517 0.74 CES2 (0.37) CES2CES1
SCHEMBL11326568 0.72 AR (0.33)
SCHEMBL11280253 0.71 CES2 (0.38) CES2CES1
SCHEMBL10938882 0.71 PDE2A (0.43) CES2
SCHEMBL206670 0.71 CES2 (0.41) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115448947-A Halogenated phosphate containing branched chain, preparation method and application thereof 恒大新能源技术(深圳)有限公司 2022-12-09 CN disclosed