SCHEMBL2891024

SCHEMBL2891024

Cn1nnnc1-c1ccc(-c2c(F)cc(N3C[C@H](CNc4ccon4)OC3=O)cc2F)cn1

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 12/20 0.53
MAOB P27338 2/20 0.46
CYP2E1 P05181 1/20 0.44
CYP2C19 P33261 2/20 0.35
CYP3A4 P08684 1/20 0.35
CALML3 P27482 3/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5216500 1.00 MAOA (0.53) MAOAMAOBCYP2E1CYP2C19CYP3A4
SCHEMBL13942418 0.91 CYP2E1 (0.52) MAOAMAOBCYP2E1CYP2C19CYP3A4
SCHEMBL2894852 0.88 MAOA (0.61) MAOAMAOBCYP2E1CYP2C19CYP3A4
SCHEMBL2899787 0.85 MAOA (0.50) MAOAMAOBCALML3
SCHEMBL6021066 0.81 MAOA (0.48) MAOAMAOBCYP2C19CALML3CYP2C9
SCHEMBL463748 0.81 MAOA (0.53) MAOAMAOBCYP2E1CYP2C19CYP3A4
SCHEMBL463449 0.79 MAOA (0.51) MAOAMAOBCYP2E1CYP2C19CYP3A4
SCHEMBL3372224 0.79 MAOA (0.57) MAOAMAOBCYP3A4
SCHEMBL463290 0.79 MAOA (0.52) MAOAMAOBCYP2E1CYP2C19CYP3A4
SCHEMBL2894839 0.77 MAOA (0.51) MAOAMAOBCYP2E1CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US claimed
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US disclosed
EP-1799677-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS Ranbaxy Laboratories Limited (IN) 2007-06-27 EP disclosed
WO-2006038100-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2006-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS OXA1L, PDK4, MLYCD MAOA 1717/4885MAOB 2038/4885CYP2E1 799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.