Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | AR | P10275 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9286611 | 0.98 | SMN1; SMN2 (0.51) | SMN1; SMN2ARHSD17B10TP53ALOX15 | |
| SCHEMBL20243714 | 0.81 | LMNA (0.58) | SMN1; SMN2ARRAB9AMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL9282405 | 0.79 | LMNA (0.57) | SMN1; SMN2ARRAB9AMAPK1MEN1 | |
| SCHEMBL17266285 | 0.78 | AR (0.54) | SMN1; SMN2ARHSD17B10TP53ALOX15 | |
| SCHEMBL22334869 | 0.78 | AR (0.54) | SMN1; SMN2ARHSD17B10TP53ALOX15 | |
| SCHEMBL18674672 | 0.78 | AR (0.54) | SMN1; SMN2ARHSD17B10TP53ALOX15 | |
| SCHEMBL18674673 | 0.78 | AR (0.54) | SMN1; SMN2ARHSD17B10TP53ALOX15 | |
| SCHEMBL4469579 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2ARHSD17B10TP53ALOX15 | |
| SCHEMBL2624023 | 0.76 | RAB9A (0.58) | SMN1; SMN2ARHSD17B10TP53ALOX15 | |
| SCHEMBL3047832 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2ARHSD17B10TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705033-B | N-heteroaryl sulfonamide derivative, preparation and application | 杭州壹瑞医药科技有限公司 | 2021-03-30 | — | — | CN | disclosed |