Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20247365 | 0.81 | CYP11B2 (0.32) | MAPT | |
| SCHEMBL11955151 | 0.75 | GAA (0.32) | — | |
| SCHEMBL21718958 | 0.71 | — | — | |
| SCHEMBL31445433 | 0.70 | HCAR2 (0.35) | MAPT | |
| SCHEMBL21718415 | 0.68 | — | — | |
| SCHEMBL21718962 | 0.67 | CYP11B1 (0.30) | — | |
| SCHEMBL21719034 | 0.67 | — | — | |
| SCHEMBL20247366 | 0.66 | PDE4D (0.34) | MAPT | |
| SCHEMBL22043375 | 0.66 | — | — | |
| SCHEMBL20974881 | 0.65 | NOTUM (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427449-A1 | VINYL INDAZOLYL COMPOUNDS | Eli Lilly and Company (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129509-A1 | VINYL INDAZOLYL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2010-11-11 | — | — | WO | disclosed |