Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31445433 | 0.71 | HCAR2 (0.35) | PDE4DUSP7CYP2D6CYP2C19MAPT | |
| SCHEMBL20247365 | 0.69 | CYP11B2 (0.32) | MAPTGAA | |
| SCHEMBL21957669 | 0.66 | ALDH1A1 (0.38) | CYP2D6CYP2C9TSHRCYP2C19MAPT | |
| SCHEMBL31445314 | 0.66 | PDE4D (0.43) | PDE4D | |
| SCHEMBL289111 | 0.66 | MAPT (0.33) | MAPT | |
| SCHEMBL17208821 | 0.66 | ATR (0.51) | PDE4DMAPTGAA | |
| SCHEMBL536167 | 0.65 | CYP3A4 (0.36) | CYP2D6CYP2C9TSHRCYP2C19GAA | |
| SCHEMBL28320432 | 0.65 | CYP19A1 (0.54) | TSHRMAPT | |
| SCHEMBL907993 | 0.65 | GAA (0.39) | CYP2D6CYP2C9TSHRCYP2C19GAA | |
| SCHEMBL1286681 | 0.65 | USP7 (0.43) | PDE4DUSP7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3333157-B1 | VINYL COMPOUNDS AS FGFR AND VEGFR INHIBITORS | HARBIN ZHENBAO PHARMACEUTICAL CO LTD (CN) | 2020-12-23 | — | — | EP | disclosed |
| EP-3333157-A1 | VINYL COMPOUNDS AS FGFR AND VEGFR INHIBITORS | Harbin Zhenbao Pharmaceutical Co., Ltd. (CN) | 2018-06-13 | — | — | EP | disclosed |