SCHEMBL28911222

SCHEMBL28911222

CO[C@@]1(O)[C@@H](CO)O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)[C@@H]1O

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 2/20 0.54
▸ HINT1 P49773 5/20 0.52
▸ NT5E P21589 1/20 0.50
▸ ADORA3 P0DMS8 1/20 0.49
▸ TAAR1 Q96RJ0 1/20 0.49
▸ GSK3A P49840 2/20 0.47
▸ RPS6KA3 P51812 2/20 0.47
▸ MAPK14 Q16539 2/20 0.47
▸ STING1 Q86WV6 2/20 0.47
▸ PDE3B Q13370 1/20 0.47
▸ PDE3A Q14432 1/20 0.47
▸ TGM2 P21980 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1374868 0.88 HINT1 (0.52) HPGDHINT1NT5EADORA3TAAR1
SCHEMBL12758342 0.88 HINT1 (0.52) HPGDHINT1NT5EADORA3TAAR1
SCHEMBL12151803 0.88 HINT1 (0.52) HPGDHINT1NT5EADORA3TAAR1
SCHEMBL7101375 0.88 ADORA3 (0.53) HPGDHINT1NT5EADORA3TAAR1
SCHEMBL29093004 0.87 NT5E (0.56) HINT1NT5ESTING1TGM2
SCHEMBL29908542 0.87 ADORA3 (0.52) HPGDHINT1NT5EADORA3TAAR1
SCHEMBL3734057 0.86 ADORA3 (0.51) HPGDHINT1NT5EADORA3TAAR1
SCHEMBL29771263 0.85 HINT1 (0.51) HPGDHINT1NT5EADORA3TAAR1
SCHEMBL3427138 0.85 ADORA3 (0.50) HPGDHINT1NT5EADORA3TAAR1
SCHEMBL18490626 0.85 ADORA3 (0.52) HPGDHINT1NT5EADORA3TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638757-A New synthesis method of 3' -methoxy nucleoside 安徽信佰生物医药科技有限公司 2025-03-18 — — CN claimed
CN-116716367-A Method for synthesizing 3' -methoxy guanosine diphosphate by multienzyme cascade reaction and application thereof 武汉糖智药业有限公司 2023-09-08 — — CN claimed
CN-112661802-B Synthetic method of 3' -methoxyguanosine 阿里生物新材料(常州)有限公司 2022-05-13 — — CN claimed
CN-112661802-A Synthetic method of 3' -methoxyguanosine 阿里生物新材料(常州)有限公司 2021-04-16 — — CN claimed
CN-119638757-A New synthesis method of 3' -methoxy nucleoside 安徽信佰生物医药科技有限公司 2025-03-18 — — CN disclosed
CN-119143815-A Preparation method of 3' -methoxy nucleoside analogue 杭州中美华东制药有限公司 2024-12-17 — — CN disclosed
CN-117105994-A Synthesis method of 3' -O-methoxy guanosine 天津全和诚科技有限责任公司 2023-11-24 — — CN disclosed
CN-116716367-A Method for synthesizing 3' -methoxy guanosine diphosphate by multienzyme cascade reaction and application thereof 武汉糖智药业有限公司 2023-09-08 — — CN disclosed
CN-116716367-A Method for synthesizing 3' -methoxy guanosine diphosphate by multienzyme cascade reaction and application thereof 武汉糖智药业有限公司 2023-09-08 — — CN disclosed
WO-2023033551-A1 MRNA CAP ANALOGUE AND USE THEREOF 한미정밀화학 주식회사 2023-03-09 — — WO disclosed
CN-112661802-B Synthetic method of 3' -methoxyguanosine 阿里生物新材料(常州)有限公司 2022-05-13 — — CN disclosed
CN-112661802-B Synthetic method of 3' -methoxyguanosine 阿里生物新材料(常州)有限公司 2022-05-13 — — CN disclosed
CN-112661802-B Synthetic method of 3' -methoxyguanosine 阿里生物新材料(常州)有限公司 2022-05-13 — — CN disclosed
CN-112661802-A Synthetic method of 3' -methoxyguanosine 阿里生物新材料(常州)有限公司 2021-04-16 — — CN disclosed
CN-112661802-A Synthetic method of 3' -methoxyguanosine 阿里生物新材料(常州)有限公司 2021-04-16 — — CN disclosed
CN-112661802-A Synthetic method of 3' -methoxyguanosine 阿里生物新材料(常州)有限公司 2021-04-16 — — CN disclosed
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