Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 5/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467736 | 0.85 | SYK (0.39) | ATRLCKAAK1CA1CA2 | |
| SCHEMBL28561049 | 0.84 | LCK (0.41) | ATRLCKCA1SYKCA12 | |
| SCHEMBL8280454 | 0.78 | ALDH1A1 (0.49) | ATRAAK1CA1CA2MEN1 | |
| SCHEMBL31290291 | 0.77 | CTSS (0.42) | ATRCA1CA2MEN1KMT2A | |
| SCHEMBL30710105 | 0.77 | LCK (0.42) | ATRLCKAAK1CA1NPC1 | |
| SCHEMBL26694465 | 0.77 | LCK (0.42) | ATRLCKAAK1CA1NPC1 | |
| SCHEMBL31716085 | 0.77 | LCK (0.45) | ATRLCKAAK1RAB9AHTT | |
| SCHEMBL26467246 | 0.75 | AAK1 (0.39) | ATRLCKAAK1CA1CA2 | |
| SCHEMBL13776174 | 0.75 | ATR (0.44) | ATRLCKAAK1CA1CA2 | |
| SCHEMBL22314427 | 0.75 | LCK (0.45) | ATRLCKAAK1SYKNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112739420-A | Phenoxy-pyridyl-pyrimidine compounds and methods of use | 基因泰克公司 | 2021-04-30 | — | — | CN | disclosed |