SCHEMBL28912201

SCHEMBL28912201

COc1ccc(-c2cc(C)ccc2S)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.50
SYK P43405 1/20 0.49
ALKBH3 Q96Q83 1/20 0.49
MAOB P27338 1/20 0.48
ABL1 P00519 1/20 0.46
ABCB1 P08183 1/20 0.46
BCR P11274 1/20 0.46
RAB9A P51151 3/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
RELA Q04206 2/20 0.46
MEN1 O00255 1/20 0.46
JAK2 O60674 1/20 0.46
LMNA P02545 1/20 0.46
NFKB1 P19838 1/20 0.46
CASP3 P42574 1/20 0.46
NFKB2 Q00653 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13932512 0.81 ACHE (0.54) ACHESYKALKBH3MAOBABL1
SCHEMBL14363373 0.79 SYK (0.61) ACHESYKALKBH3MAOBABL1
SCHEMBL29233386 0.78 ACHE (0.50) ACHESYKALKBH3MAOBABL1
SCHEMBL24061159 0.78 L3MBTL1 (0.50) ACHESYKALKBH3MAOBABL1
SCHEMBL12345146 0.77 ACHE (0.54) ACHESYKALKBH3MAOBABL1
SCHEMBL28183343 0.76 ALKBH3 (0.51) ACHESYKALKBH3MAOBABL1
SCHEMBL7434020 0.76 HDAC7 (0.47) MAOBRAB9AMAPTKMT2AMEN1
SCHEMBL28762102 0.76 BACE1 (0.50) ABL1ABCB1BCRRAB9AMAPT
SCHEMBL7278655 0.75 ABL1 (0.60) MAOBABL1ABCB1BCRRAB9A
SCHEMBL12508085 0.74 CYP2C19 (0.54) ACHESYKALKBH3MAOBABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107298650-B Heterocyclic carboxylic acid amide ligands and their use in copper catalyzed aryl halide coupling reactions 浙江中科创越药业有限公司 2022-11-15 CN disclosed