Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 6/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 4/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22554309 | 0.81 | ABL1 (0.44) | NUDT1PRKCIDAOABL1SRC | |
| SCHEMBL30731054 | 0.81 | ABL1 (0.44) | NUDT1PRKCIDAOABL1SRC | |
| SCHEMBL30731078 | 0.79 | NUDT1 (0.48) | NUDT1BRAF | |
| SCHEMBL3603471 | 0.79 | NUDT1 (0.48) | NUDT1BRAF | |
| SCHEMBL22554070 | 0.76 | DAO (0.44) | NUDT1PRKCICCNKCDK12DAO | |
| SCHEMBL30731002 | 0.76 | DAO (0.44) | NUDT1PRKCICCNKCDK12DAO | |
| SCHEMBL22554174 | 0.73 | NUDT1 (0.43) | NUDT1PRKCICCNKCDK12 | |
| SCHEMBL22554098 | 0.71 | DAO (0.45) | NUDT1CCNKCDK12DAO | |
| SCHEMBL30731058 | 0.71 | NUDT1 (0.42) | NUDT1CCNKCDK12 | |
| SCHEMBL22570933 | 0.71 | NUDT1 (0.42) | NUDT1CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088157-A | Aryl-bipyridine amine derivatives as phosphoinositide kinase inhibitors | 拉文纳制药公司 | 2020-12-15 | — | — | CN | disclosed |