SCHEMBL28912656

SCHEMBL28912656

CNc1ncnc2c1ncn2C1C[C@H](O)[C@@H](C[O])O1

nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 5/20 0.69
HIF1A Q16665 1/20 0.57
SLC29A1 Q99808 1/20 0.56
YTHDC1 Q96MU7 1/20 0.52
ADORA1 P30542 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21011280 0.90 HIF1A (0.71) ADORA3HIF1ASLC29A1
SCHEMBL17920432 0.90 ADORA3 (0.67) ADORA3HIF1ASLC29A1YTHDC1ADORA1
SCHEMBL548570 0.90 HIF1A (0.71) ADORA3HIF1ASLC29A1
SCHEMBL6267085 0.90 HIF1A (0.71) ADORA3HIF1ASLC29A1
SCHEMBL6267089 0.90 HIF1A (0.71) ADORA3HIF1ASLC29A1
SCHEMBL23982373 0.90 HIF1A (0.71) ADORA3HIF1ASLC29A1
SCHEMBL548569 0.90 HIF1A (0.71) ADORA3HIF1ASLC29A1
SCHEMBL11986894 0.90 ADORA3 (0.67) ADORA3HIF1ASLC29A1YTHDC1ADORA1
SCHEMBL31685679 0.86 ADORA3 (0.62) ADORA3
SCHEMBL6513690 0.85 ADORA3 (0.61) ADORA3HIF1ASLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778388-B Nucleoside analogue and preparation method and application thereof 大连医科大学 2022-08-23 CN disclosed
CN-112778388-A Nucleoside analogue and preparation method and application thereof 大连医科大学 2021-05-11 CN disclosed