SCHEMBL28912876

SCHEMBL28912876

Brc1ccc(C(c2ccc(Br)cc2)(c2ccc(Br)cc2)c2ccc(C(c3ccc(Br)cc3)(c3ccc(Br)cc3)c3ccc(Br)cc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.57
CA2 P00918 4/20 0.42
CA1 P00915 3/20 0.42
CA5A P35218 1/20 0.42
CA9 Q16790 1/20 0.42
ALDH1A1 P00352 4/20 0.42
ALOX15 P16050 2/20 0.42
MAPK1 P28482 2/20 0.42
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
OGG1 O15527 1/20 0.35
CYP19A1 P11511 1/20 0.33
HTR2A P28223 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
IDO1 P14902 1/20 0.32
SLC22A2 O15244 1/20 0.32
SLC22A1 O15245 1/20 0.32
SLC22A3 O75751 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440244 1.00 CYP2A6 (0.57) CYP2A6CA2CA1CA5ACA9
SCHEMBL2700861 0.91 ALDH1A1 (0.52) CYP2A6CA2CA1CA5ACA9
SCHEMBL3956177 0.88 ALDH1A1 (0.53) CYP2A6CA2CA1CA5ACA9
SCHEMBL3083376 0.88 ALDH1A1 (0.53) CYP2A6CA2CA1CA5ACA9
SCHEMBL17941356 0.88 ALDH1A1 (0.53) CYP2A6CA2CA1CA5ACA9
SCHEMBL3079657 0.86 CYP2A6 (0.42) CYP2A6CA2CA1CA5ACA9
SCHEMBL13149684 0.86 MEN1 (0.42) CYP2A6CA2CA1CA5ACA9
SCHEMBL13149673 0.86 ALOX15 (0.68) CYP2A6CA2CA1CA5ACA9
SCHEMBL452831 0.86 ALDH1A1 (0.68) CYP2A6CA2CA1CA5ACA9
SCHEMBL3092338 0.86 CYP2A6 (0.42) CYP2A6CA2CA1CA5ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112724373-B Functional organic porous polymer and preparation method and application thereof 山东大学 2021-09-21 CN claimed
CN-112724373-A Functional organic porous polymer and preparation method and application thereof 山东大学 2021-04-30 CN claimed
CN-112724373-B Functional organic porous polymer and preparation method and application thereof 山东大学 2021-09-21 CN disclosed
CN-112724373-A Functional organic porous polymer and preparation method and application thereof 山东大学 2021-04-30 CN disclosed