Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 2/20 | 0.42 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28558968 | 0.99 | ITGAV (0.41) | ITGAVITGB6PRMT5WDR77GPR119 | |
| SCHEMBL20481266 | 0.88 | ITGAV (0.42) | ITGAVITGB6PRMT5WDR77GPR119 | |
| SCHEMBL20481267 | 0.88 | ITGAV (0.42) | ITGAVITGB6PRMT5WDR77GPR119 | |
| SCHEMBL30336019 | 0.88 | ITGAV (0.42) | ITGAVITGB6PRMT5WDR77GPR119 | |
| SCHEMBL28334819 | 0.87 | LMNA (0.36) | ITGAVITGB6PDE10A | |
| SCHEMBL28562358 | 0.87 | LMNA (0.36) | ITGAVITGB6PDE10A | |
| SCHEMBL21767609 | 0.87 | ITGAV (0.41) | ITGAVITGB6PRMT5WDR77GPR119 | |
| SCHEMBL21767607 | 0.87 | ITGAV (0.41) | ITGAVITGB6PRMT5WDR77GPR119 | |
| SCHEMBL28565963 | 0.86 | LMNA (0.36) | ITGAVITGB6PDE10A | |
| SCHEMBL28571865 | 0.85 | PRMT5 (0.39) | ITGAVITGB6PRMT5WDR77GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805001-A | Inhibition of alpha v beta 6 integrins | 莫菲克医疗股份有限公司 | 2021-05-14 | — | — | CN | disclosed |