SCHEMBL28913091

SCHEMBL28913091

Cc1cc(F)c(N)cc1F.F[B-](F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
CYP3A4 P08684 2/20 0.35
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.35
ACHE P22303 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
CASP1 P29466 1/20 0.31
CD44 P16070 1/20 0.31
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29838774 0.93 ALDH1A1 (0.40) ALDH1A1CYP3A4TSHRMAPK1ACHE
SCHEMBL1479690 0.93 ALDH1A1 (0.40) ALDH1A1CYP3A4TSHRMAPK1ACHE
SCHEMBL28566476 0.91 CYP3A4 (0.40) ALDH1A1CYP3A4TSHRMAPK1ACHE
SCHEMBL29538146 0.83 CYP3A4 (0.48) ALDH1A1CYP3A4TSHRMAPK1ACHE
SCHEMBL16660691 0.82 CYP3A4 (0.46) ALDH1A1CYP3A4TSHRMAPK1ACHE
SCHEMBL3873719 0.79 CYP3A4 (0.55) ALDH1A1CYP3A4TSHRMAPK1ACHE
SCHEMBL405476 0.79 CD44 (0.48) ALDH1A1CYP3A4TSHRMAPK1ACHE
SCHEMBL29791306 0.79 CYP3A4 (0.55) ALDH1A1CYP3A4TSHRMAPK1ACHE
SCHEMBL457125 0.77 CYP3A4 (0.52) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL29358157 0.77 CYP3A4 (0.52) ALDH1A1CYP3A4TSHRMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112851493-B Preparation method of 2,4, 5-trifluoro phenylacetic acid 台州臻挚生物科技有限公司 2022-09-06 CN disclosed
CN-112851493-A Preparation method of 2,4, 5-trifluorophenylacetic acid 杭州臻挚生物科技有限公司 2021-05-28 CN disclosed