Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17042294 | 0.87 | PBRM1 (0.38) | PBRM1ALDH1A1GAA | |
| SCHEMBL15224589 | 0.79 | PBRM1 (0.38) | PBRM1ALDH1A1GAA | |
| SCHEMBL3225154 | 0.78 | SLC2A1 (0.38) | PBRM1ALDH1A1GAA | |
| SCHEMBL24787 | 0.76 | CA1 (0.32) | TSHRKDM4ECYP3A4MAPTBLM | |
| SCHEMBL15224820 | 0.76 | PBRM1 (0.36) | PBRM1ALDH1A1GAA | |
| SCHEMBL139926 | 0.74 | ESR1 (0.41) | PBRM1LMNAALDH1A1GAA | |
| SCHEMBL27657818 | 0.74 | MEN1 (0.38) | MAPTALDH1A1GAA | |
| SCHEMBL21027532 | 0.74 | ALDH1A1 (0.32) | ALDH1A1GAA | |
| SCHEMBL29913553 | 0.74 | ESR1 (0.39) | PBRM1LMNAALDH1A1GAA | |
| SCHEMBL8985414 | 0.74 | ALDH1A1 (0.32) | CYP2C19ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109982993-B | Asymmetrically substituted dienyl diphenyl ethers, their preparation and use | 赢创运营有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-108349861-B | Alkenylphenoxy-substituted 1, 1-diphenylethylenes, process for their preparation and their use | 赢创运营有限公司 | 2021-07-20 | — | — | CN | disclosed |
| CN-108137458-B | [ (2-ethoxy-5-trans-1-propen-1-yl) -phenoxy ] -end-capping compounds | 赢创运营有限公司 | 2021-01-05 | — | — | CN | disclosed |