SCHEMBL28913604

SCHEMBL28913604

CC(=O)NCC(=O)OC(=O)[C@@H]1CCCN1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRCP P42785 2/20 0.41
HTR2C P28335 4/20 0.37
TLR2 O60603 2/20 0.36
KDM4E B2RXH2 1/20 0.35
DPP7 Q9UHL4 1/20 0.35
DPP4 P27487 4/20 0.34
DPP8 Q6V1X1 1/20 0.34
HTR2B P41595 2/20 0.34
TERT O14746 1/20 0.33
HTR2A P28223 1/20 0.33
PREP P48147 1/20 0.33
FAP Q12884 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27953007 0.86 PRCP (0.49) PRCPHTR2CTLR2KDM4EDPP7
SCHEMBL10798986 0.85 PRCP (0.37) PRCPHTR2CTLR2KDM4EDPP7
SCHEMBL7364623 0.84 PRCP (0.40) PRCPHTR2CTLR2KDM4EDPP7
SCHEMBL7263635 0.83 KMT2A (0.41) PRCPHTR2CTLR2KDM4EDPP4
SCHEMBL10798003 0.82 PRCP (0.37) PRCPHTR2CTLR2KDM4EDPP4
SCHEMBL14876502 0.82 PRCP (0.37) PRCPHTR2CTLR2KDM4EDPP7
Hydrochloric Acid SCHEMBL10976648 0.82 MEN1 (0.40) PRCPHTR2CTLR2KDM4EDPP4
SCHEMBL30265157 0.80 PRCP (0.44) PRCPTLR2KDM4EDPP7DPP4
SCHEMBL9362980 0.80 PRCP (0.44) PRCPTLR2KDM4EDPP7DPP4
SCHEMBL542283 0.79 NOS2 (0.39) PRCPHTR2CDPP7DPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112898293-B Bioluminescent probe for detecting fibroblast activation protein, and preparation method and application thereof 徐州医科大学 2022-04-29 CN disclosed
CN-112898293-A Bioluminescent probe for detecting fibroblast activation protein, and preparation method and application thereof 徐州医科大学 2021-06-04 CN disclosed