Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28913604 | 0.84 | PRCP (0.41) | PRCPDPP7TLR2KDM4EHTR2C | |
| SCHEMBL9362980 | 0.83 | PRCP (0.44) | PRCPDPP7TLR2NOS2NOS3 | |
| SCHEMBL30265157 | 0.83 | PRCP (0.44) | PRCPDPP7TLR2NOS2NOS3 | |
| SCHEMBL27953007 | 0.83 | PRCP (0.49) | PRCPDPP7TLR2KDM4EHTR2C | |
| SCHEMBL542283 | 0.81 | NOS2 (0.39) | PRCPDPP7NOS2NOS3NOS1 | |
| SCHEMBL7263635 | 0.80 | KMT2A (0.41) | PRCPTLR2KDM4EHTR2CDPP4 | |
| SCHEMBL5633667 | 0.80 | DPP4 (0.39) | PRCPDPP7NOS2NOS3NOS1 | |
| SCHEMBL10798003 | 0.79 | PRCP (0.37) | PRCPTLR2NOS2NOS3NOS1 | |
| SCHEMBL599792 | 0.79 | ALDH1A1 (0.45) | PRCPDPP7TLR2NOS2NOS3 | |
| SCHEMBL19066799 | 0.79 | PRCP (0.38) | PRCPDPP7TLR2NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4514391-A | HYPOTENSIVE AGENTS; ANALGESICS | E. R. SQUIBB & SONS, INC. (US) | 1985-04-30 | — | — | US | disclosed |
| EP-0132304-A2 | Hydroxy substituted peptide compounds | E.R. Squibb & Sons, Inc. (US) | 1985-01-30 | — | — | EP | disclosed |
| US-4432971-A | HYPOTENSIVE AGENTS AND ANGIOTENSIN INHIBITION | E. R. SQUIBB & SONS, INC. (US) | 1984-02-21 | — | — | US | disclosed |
| EP-0071544-A1 | Phosphonamidate compounds | E.R. Squibb & Sons, Inc. (US) | 1983-02-09 | — | — | EP | disclosed |