Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 11/20 | 0.55 |
| ▸ | ACE | P12821 | 4/20 | 0.55 |
| ▸ | MMEL1 | Q495T6 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28654586 | 0.89 | MME (0.57) | MMEACEMMEL1 | |
| SCHEMBL17746035 | 0.89 | MME (0.65) | MMEACEMMEL1 | |
| SCHEMBL21239962 | 0.89 | MME (0.65) | MMEACEMMEL1 | |
| SCHEMBL1909815 | 0.87 | MME (0.59) | MMEACEMMEL1 | |
| SCHEMBL1908574 | 0.87 | MME (0.59) | MMEACEMMEL1 | |
| SCHEMBL24408248 | 0.87 | MME (0.59) | MMEACEMMEL1 | |
| SCHEMBL21727312 | 0.86 | MME (0.64) | MMEACEMMEL1 | |
| SCHEMBL25129465 | 0.86 | MME (0.64) | MMEACEMMEL1 | |
| SCHEMBL28344119 | 0.85 | MMEL1 (0.58) | MMEACEMMEL1 | |
| Sacubitril SCHEMBL22420467 | 0.84 | MME (0.77) | MMEACEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107468685-B | Pharmaceutical composition and compound for treating hypertension and heart failure | 科贝源(北京)生物医药科技有限公司 | 2021-06-01 | — | — | CN | claimed |
| CN-107468685-B | Pharmaceutical composition and compound for treating hypertension and heart failure | 科贝源(北京)生物医药科技有限公司 | 2021-06-01 | — | — | CN | disclosed |