Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2891472 | 1.00 | KDM4E (0.41) | KDM4EFDPSPDE4BAKR1C3XDH | |
| SCHEMBL3632799 | 0.90 | KDM4E (0.43) | KDM4EFDPSPDE4BAKR1C3XDH | |
| SCHEMBL3632523 | 0.90 | KDM4E (0.43) | KDM4EFDPSPDE4BAKR1C3XDH | |
| SCHEMBL3632522 | 0.90 | KDM4E (0.43) | KDM4EFDPSPDE4BAKR1C3XDH | |
| SCHEMBL2891475 | 0.88 | TUBB4A (0.41) | KDM4EFDPSPDE4BAKR1C3XDH | |
| SCHEMBL4220330 | 0.81 | ALOX5 (0.40) | KDM4EFDPSPDE4BAKR1C3XDH | |
| SCHEMBL4220323 | 0.81 | ALOX5 (0.40) | KDM4EFDPSPDE4BAKR1C3XDH | |
| SCHEMBL4220328 | 0.81 | ALOX5 (0.40) | KDM4EFDPSPDE4BAKR1C3XDH | |
| SCHEMBL68303 | 0.80 | KDM4E (0.42) | KDM4EAKR1C3XDHKMT2AESR1 | |
| SCHEMBL4215918 | 0.80 | KDM4E (0.42) | KDM4EAKR1C3XDHKMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357819-B2 | Method for the synthesis of (Z)-3-[2-butoxy-3′-(3-heptyl-1-methyl-ureido)-biphenyl-4-yl]-2-methoxy-acrylic acid | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-01-22 | — | — | US | disclosed |
| US-20100286430-A1 | METHOD FOR THE SYNTHESIS OF (Z)-3-[2-BUTOXY-3'-(3-HEPTYL-1-METHYL-UREIDO)-BIPHENYL-4-YL]-2-METHOXY-ACRYLIC ACID | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286430-A1 | METHOD FOR THE SYNTHESIS OF (Z)-3-[2-BUTOXY-3'-(3-HEPTYL-1-METHYL-UREIDO)-BIPHENYL-4-YL]-2-METHOXY-ACRYLIC ACID | AZI2, UGT1A6, UGT1A3 | KDM4E 253/4885FDPS 702/4885PDE4B 4032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.