SCHEMBL28914873

SCHEMBL28914873

OC(c1ccc[nH]1)C(F)F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5756561 0.77 KDM5A (0.33) DAOHDAC8HDAC6
SCHEMBL8526058 0.76 DAO (0.30) DAOHDAC8HDAC6
SCHEMBL10366551 0.75 DAO (0.37) DAOHDAC8HDAC6
SCHEMBL4409393 0.75
SCHEMBL3295069 0.75
Hydrogen Sulfide SCHEMBL28275355 0.73
SCHEMBL1587572 0.73 DAO (0.32) DAOHDAC8HDAC6
SCHEMBL3817972 0.72 FKBP5 (0.38) DAOHDAC8HDAC6
SCHEMBL28863955 0.71
SCHEMBL27343778 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115490628-B Preparation method of difluoroethanol compound 五邑大学 2024-05-28 CN disclosed
CN-115490628-A Preparation method of difluoroethanol compound 五邑大学 2022-12-20 CN disclosed