Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4662942 | 0.87 | PTPRB (0.45) | PTPRBPKMKDM4ETHRBHTT | |
| SCHEMBL561888 | 0.83 | HTT (0.44) | PTPRBPKMKDM4ETHRBHTT | |
| SCHEMBL561889 | 0.83 | HTT (0.44) | PTPRBPKMKDM4ETHRBHTT | |
| SCHEMBL26447908 | 0.80 | PKM (0.41) | PTPRBPKMKDM4ETHRBHTT | |
| SCHEMBL26179175 | 0.79 | PKM (0.42) | PTPRBPKMKDM4ETHRBHTT | |
| SCHEMBL895834 | 0.79 | SMN1; SMN2 (0.40) | PTPRBPKMKDM4ETHRBHTT | |
| SCHEMBL26447892 | 0.79 | PTPRB (0.42) | PTPRBPKMKDM4ETHRBHTT | |
| SCHEMBL17439188 | 0.78 | PKM (0.49) | PTPRBPKMKDM4ETHRBHTT | |
| SCHEMBL561048 | 0.78 | PTPRB (0.45) | PTPRBPKMKDM4ETHRBHTT | |
| SCHEMBL28914988 | 0.77 | ALDH1A1 (0.65) | PTPRBALDH1A1RECQLATMCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490606-A | Method for preparing medical intermediate from 2-chloromethylene-diethyl malonate | 安徽泽升科技有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-115490606-A | Method for preparing medical intermediate from 2-chloromethylene-diethyl malonate | 安徽泽升科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-115490606-A | Method for preparing medical intermediate from 2-chloromethylene-diethyl malonate | 安徽泽升科技有限公司 | 2022-12-20 | — | — | CN | disclosed |