Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 17/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933143 | 1.00 | ERN1 (0.48) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL27867837 | 0.86 | ERN1 (0.45) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL9787541 | 0.85 | ERN1 (0.48) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL28678695 | 0.85 | ERN1 (0.51) | ERN1CA1CA2 | |
| SCHEMBL29365717 | 0.85 | ERN1 (0.51) | ERN1CA1CA2 | |
| SCHEMBL28843543 | 0.84 | ERN1 (0.46) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL27306404 | 0.82 | ALDH1A1 (0.42) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL31166894 | 0.82 | ALDH1A1 (0.42) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL29933260 | 0.82 | ERN1 (0.47) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL7380240 | 0.81 | ERN1 (0.47) | ERN1CA1CA2TRIM24TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812113-B | Immunomodulatory compounds, compositions and uses thereof | 杭州和正医药有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-112812113-A | Immunomodulatory compounds, compositions and uses thereof | 杭州和正医药有限公司 | 2021-05-18 | — | — | CN | disclosed |