Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 18/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28678695 | 0.85 | ERN1 (0.51) | ERN1CA1CA2 | |
| SCHEMBL29365717 | 0.85 | ERN1 (0.51) | ERN1CA1CA2 | |
| SCHEMBL9787541 | 0.85 | ERN1 (0.48) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL4655024 | 0.82 | ALDH1A1 (0.42) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL27189181 | 0.82 | ALDH1A1 (0.42) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL27189236 | 0.82 | ERN1 (0.47) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL29933143 | 0.81 | ERN1 (0.48) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL28915744 | 0.81 | ERN1 (0.48) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL5759448 | 0.79 | PRKDC (0.44) | ERN1CA1CA2TRIM24TYR | |
| SCHEMBL310426 | 0.79 | ALDH1A1 (0.42) | ERN1CA1CA2TRIM24TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102731378-A | Preparation method of 3-hydroxyl-N-(3,5-dichloropyridine-4-group)-4-(difluoromethoxy)benzamide | SICHUAN SHUZHONG PHARMACEUTICAL CO LTD | 2012-10-17 | — | — | CN | disclosed |
| EP-0934280-A1 | PDE IV INHIBITING 2-CYANOIMINOIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998014432-A1 | PDE IV INHIBITING 2-CYANOIMINOIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-04-09 | — | — | WO | disclosed |