Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19716281 | 0.85 | NPC1 (0.48) | MAPTKDM4ESMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL29286714 | 0.84 | ALDH1A1 (0.37) | MAPTSMN1; SMN2ALDH1A1MAPK1TSHR | |
| SCHEMBL4285291 | 0.83 | TP53 (0.44) | MAPTKDM4ESMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL3846829 | 0.83 | GAA (0.44) | MAPTKDM4ESMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL28916204 | 0.82 | KDM4E (0.42) | MAPTKDM4ESMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL4284526 | 0.80 | KDM4E (0.42) | MAPTKDM4ESMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL3848405 | 0.80 | KDM4E (0.36) | MAPTKDM4ESMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL5359650 | 0.76 | MAPT (0.41) | MAPTKDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL687803 | 0.75 | NOTUM (0.44) | MAPTKDM4ESMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL3848554 | 0.75 | LIPE (0.37) | MAPTKDM4ESMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115485279-A | Antibacterial 8-phenylamino-3- (pyrazol-4-yl) imidazo [1,2-a ] pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2022-12-16 | — | — | CN | disclosed |