Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 14/20 | 0.65 |
| ▸ | P2RX1 | P51575 | 7/20 | 0.61 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.61 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | IKBKB | O14920 | 1/20 | 0.61 |
| ▸ | CHUK | O15111 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | FLT3 | P36888 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MYLK | Q15746 | 1/20 | 0.61 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.61 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.58 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28916405 | 0.89 | TMPRSS4 (0.63) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL14886093 | 0.83 | TMPRSS4 (0.76) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL28916379 | 0.82 | TMPRSS4 (0.60) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL30087008 | 0.81 | TMPRSS4 (0.77) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL28916402 | 0.81 | TMPRSS4 (0.77) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL330166 | 0.79 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL28916376 | 0.79 | TMPRSS4 (0.61) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL330023 | 0.78 | TMPRSS4 (0.83) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL330413 | 0.77 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL329995 | 0.77 | TMPRSS4 (0.73) | TMPRSS4P2RX1P2RX4P2RX7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504902-A | 5-chloro salicylamide derivatives, preparation method thereof and application thereof as medicaments | 广东药科大学 | 2022-12-23 | — | — | CN | claimed |
| CN-115504902-A | 5-chloro salicylamide derivatives, preparation method thereof and application thereof as medicaments | 广东药科大学 | 2022-12-23 | — | — | CN | disclosed |