Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | CES2 | O00748 | 2/20 | 0.60 |
| ▸ | CES1 | P23141 | 2/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28916574 | 0.98 | HPGD (0.68) | HPGDSMN1; SMN2HTTALOX15L3MBTL1 | |
| SCHEMBL28614894 | 0.85 | BLM (0.62) | HPGDSMN1; SMN2ALDH1A1MAPTCES2 | |
| SCHEMBL29209365 | 0.83 | HPGD (0.66) | HPGDSMN1; SMN2HTTALOX15L3MBTL1 | |
| SCHEMBL2534411 | 0.82 | HPGD (1.00) | HPGDSMN1; SMN2HTTALOX15L3MBTL1 | |
| SCHEMBL2535536 | 0.81 | HPGD (0.96) | HPGDSMN1; SMN2HTTALOX15L3MBTL1 | |
| SCHEMBL28916562 | 0.80 | CES2 (0.56) | HPGDSMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL18352035 | 0.79 | SMN1; SMN2 (0.49) | HPGDSMN1; SMN2HTTALOX15L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5213430 | 0.79 | HPGD (0.93) | HPGDSMN1; SMN2HTTALOX15L3MBTL1 | |
| SCHEMBL28916556 | 0.79 | RAB9A (0.57) | HPGDSMN1; SMN2ALDH1A1MAPTCES2 | |
| SCHEMBL14019821 | 0.77 | HPGD (0.87) | HPGDSMN1; SMN2HTTALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504946-B | Method for synthesizing alpha-ketoamide compound | 武汉工程大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-115504946-A | Method for synthesizing alpha-keto amide compound | 武汉工程大学 | 2022-12-23 | — | — | CN | disclosed |