Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25224343 | 1.00 | NPC1 (0.37) | NPC1SMN1; SMN2RAB9AHIF1APKM | |
| SCHEMBL23965620 | 0.90 | HIF1A (0.45) | NPC1SMN1; SMN2RAB9AHIF1APKM | |
| SCHEMBL30168077 | 0.90 | HIF1A (0.45) | NPC1SMN1; SMN2RAB9AHIF1APKM | |
| SCHEMBL23965621 | 0.89 | ALDH1A1 (0.38) | NPC1SMN1; SMN2RAB9AHIF1APKM | |
| SCHEMBL30168064 | 0.89 | GAA (0.36) | NPC1SMN1; SMN2RAB9AHIF1APKM | |
| SCHEMBL30104137 | 0.89 | HIF1A (0.38) | NPC1SMN1; SMN2RAB9AHIF1APKM | |
| SCHEMBL23965569 | 0.89 | GAA (0.36) | NPC1SMN1; SMN2RAB9AHIF1APKM | |
| SCHEMBL30214721 | 0.85 | HIF1A (0.41) | NPC1SMN1; SMN2RAB9AHIF1APKM | |
| SCHEMBL23983965 | 0.84 | PKM (0.39) | NPC1SMN1; SMN2RAB9AHIF1APKM | |
| SCHEMBL25243846 | 0.83 | PPARA (0.43) | NPC1SMN1; SMN2RAB9AHIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115484821-A | Use of strobilurin-type compounds to control phytopathogenic fungi containing the amino acid substitution F129L in the mitochondrial cytochrome b protein conferring tolerance to Qo inhibitor III | 巴斯夫欧洲公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-115484820-A | Use of strobilurin-type compounds to control phytopathogenic fungi containing in the mitochondrial cytochrome b protein an amino acid substitution F129L conferring tolerance to Qo inhibitor I | 巴斯夫欧洲公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-115460920-A | Use of strobilurin-type compounds to control phytopathogenic fungi containing in the mitochondrial cytochrome b protein an amino acid substitution F129L conferring tolerance to Qo inhibitor II | 巴斯夫欧洲公司 | 2022-12-09 | — | — | CN | disclosed |