SCHEMBL28918992

SCHEMBL28918992

O=Cc1cc(-c2ccccc2N(c2ccccc2)c2ccccc2)c(C=O)cc1-c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
APP P05067 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
XDH P47989 1/20 0.31
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30
KCNA3 P22001 1/20 0.30
NR3C1 P04150 1/20 0.30
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30129810 0.82 APP (0.47) RAB9ANPC1APPMEN1KMT2A
SCHEMBL4728239 0.81 KMT2A (0.39) RAB9ANPC1APPMEN1KMT2A
SCHEMBL31717974 0.79 KMT2A (0.50) RAB9ANPC1MEN1KMT2ALMNA
SCHEMBL30021343 0.77 ALDH1A1 (0.38) MEN1KMT2ATDP1KCNA3
SCHEMBL2784066 0.77 ALDH1A1 (0.38) MEN1KMT2ATDP1KCNA3
SCHEMBL28846480 0.77 ALDH1A1 (0.38) MEN1KMT2ATDP1KCNA3
SCHEMBL733459 0.77 ALDH1A1 (0.41) MEN1KMT2ATDP1KCNA3
SCHEMBL29511964 0.77 ALDH1A1 (0.41) MEN1KMT2ATDP1KCNA3
SCHEMBL20320139 0.76 DRD1 (0.45) APPKCNA3
SCHEMBL16577712 0.75 ALDH1A1 (0.43) MEN1KMT2ATDP1KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115504930-B Bipyridyl aggregation-induced emission compound with multiple stimulus responses, and preparation method and application thereof 合肥工业大学 2024-07-02 CN disclosed
CN-115504930-A Bipyridinyl aggregation-induced emission compound with multiple stimulus responses and preparation method and application thereof 合肥工业大学 2022-12-23 CN disclosed