SCHEMBL4728239

SCHEMBL4728239

O=Cc1ccccc1N(c1ccccc1)c1ccccc1-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.39
LMNA P02545 2/20 0.39
MEN1 O00255 2/20 0.39
THRB P10828 1/20 0.39
BLM P54132 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
APP P05067 1/20 0.35
XDH P47989 1/20 0.35
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
TRIM24 O15164 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
GAA P10253 1/20 0.33
GRIN2D O15399 2/20 0.32
GRIN3B O60391 2/20 0.32
GRIN1 Q05586 2/20 0.32
GRIN2A Q12879 2/20 0.32
GRIN2B Q13224 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31298129 0.88 KMT2A (0.50) KMT2ALMNAMEN1THRBBLM
SCHEMBL50149 0.84 KMT2A (0.50) KMT2ALMNAMEN1THRBBLM
SCHEMBL21615006 0.84 ALDH1A1 (0.41) KMT2AMEN1TDP1ALDH1A1KCNA3
SCHEMBL14196524 0.82 NFE2L2 (0.41) KMT2AMEN1TDP1APPALDH1A1
SCHEMBL28918992 0.81 RAB9A (0.35) KMT2ALMNAMEN1THRBBLM
SCHEMBL31058396 0.80 LMNA (0.46) KMT2ALMNAMEN1THRBBLM
SCHEMBL5918726 0.80 ALDH1A1 (0.46) KMT2AMEN1TDP1APPALDH1A1
SCHEMBL29511964 0.80 ALDH1A1 (0.41) KMT2AMEN1TDP1ALDH1A1KCNA3
SCHEMBL733459 0.80 ALDH1A1 (0.41) KMT2AMEN1TDP1ALDH1A1KCNA3
SCHEMBL20320139 0.78 DRD1 (0.45) APPALDH1A1KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1519236-B1 Organophotoreceptor with an epoxy-modified charge transport compound having an azine group SAMSUNG ELECTRONICS CO LTD (KR) 2008-04-23 EP disclosed