Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919043 | 0.92 | ALDH1A1 (0.52) | P2RY12ALDH1A1MAPTLMNATP53 | |
| SCHEMBL28919053 | 0.86 | MAPT (0.61) | ALDH1A1MAPTLMNATP53CYP2C9 | |
| SCHEMBL28919025 | 0.82 | NR1H4 (0.58) | ALDH1A1MAPTLMNATP53NR1H4 | |
| SCHEMBL30080500 | 0.82 | NR1H4 (0.58) | ALDH1A1MAPTLMNATP53NR1H4 | |
| SCHEMBL1398494 | 0.81 | ALDH1A1 (0.61) | P2RY12ALDH1A1MAPTLMNATP53 | |
| SCHEMBL28919037 | 0.80 | MAPT (0.52) | ALDH1A1MAPTLMNATP53CYP2C9 | |
| SCHEMBL30725450 | 0.79 | NR1H4 (0.63) | ALDH1A1MAPTLMNATP53NR1H4 | |
| SCHEMBL29174559 | 0.79 | NR1H4 (0.63) | ALDH1A1MAPTLMNATP53NR1H4 | |
| SCHEMBL28599298 | 0.78 | PCSK9 (0.50) | ALDH1A1MAPTLMNATP53THRB | |
| SCHEMBL29519544 | 0.78 | PCSK9 (0.50) | ALDH1A1MAPTLMNATP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |