Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28599298 | 1.00 | PCSK9 (0.50) | PCSK9THRBKMT2ALMNAMAPT | |
| SCHEMBL28603507 | 0.92 | THRB (0.53) | PCSK9THRBKMT2ALMNAMAPT | |
| SCHEMBL28917875 | 0.82 | THRB (0.49) | PCSK9THRBKMT2ALMNAMAPT | |
| SCHEMBL28919046 | 0.78 | P2RY12 (0.56) | THRBLMNAMAPTALDH1A1TP53 | |
| SCHEMBL28919024 | 0.77 | POLB (0.49) | THRBKMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL28919053 | 0.76 | MAPT (0.61) | THRBKMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL28590359 | 0.74 | KMT2A (0.49) | KMT2ALMNAMAPTTP53POLB | |
| SCHEMBL28919043 | 0.73 | ALDH1A1 (0.52) | THRBLMNAMAPTALDH1A1TP53 | |
| SCHEMBL29043227 | 0.71 | PIK3CD (0.52) | KMT2ALMNAMAPTALDH1A1POLB | |
| SCHEMBL29043232 | 0.71 | NR1H4 (0.46) | KMT2ALMNAMAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121467-B | Benzothiazole derivative and medical application thereof | 河北师范大学 | 2022-03-29 | — | — | CN | disclosed |