Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | KRAS | P01116 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28606019 | 0.87 | CXCL12 (0.74) | — | |
| SCHEMBL25203675 | 0.84 | TUBB4A (0.67) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL9339706 | 0.83 | MAPT (0.68) | NPC1MEN1KMT2ALMNAGAA | |
| SCHEMBL9339697 | 0.83 | MAPT (0.68) | NPC1MEN1KMT2ALMNAGAA | |
| SCHEMBL499504 | 0.82 | MEN1 (0.67) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL499505 | 0.82 | MEN1 (0.67) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL10497875 | 0.81 | ABCG2 (0.81) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL10497877 | 0.81 | ABCG2 (0.81) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL28608357 | 0.81 | PPARG (0.70) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL25208931 | 0.81 | MCL1 (0.77) | NPC1MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113230240-B | 1,3-diphenylprop-2-en-1-one derivative and application thereof | 广州医科大学 | 2022-12-27 | — | — | CN | disclosed |
| CN-113230240-A | 1, 3-diphenylprop-2-en-1-one derivative and application thereof | 广州医科大学 | 2021-08-10 | — | — | CN | disclosed |